Acetylcholine receptor antibodies in a patient with sensory neuropathy.

Abstract

Antibodies to acetylcholine receptor (AChR) are detected in the vast majority of patients with generalized myasthenia gravis (MG) and are rarely detected in significant titer in other autoimmune diseases. We report a patient with an axonal predominately sensory neuropathy for over 12 years with persistent binding and modulating AChR antibodies as well as striational muscle antibodies with no evidence of MG or any neoplastic disease.

• Authors: Shitiz Sriwastava, Robert P Lisak
• Journal: Journal of neuroimmunology (J Neuroimmunol) Vol. 359 Pg. 577692 (10 15 2021) ISSN: 1872-8421 [Electronic] Netherlands
• PMID: 34403864 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2021 Elsevier B.V. All rights reserved.

Chemical References

• Autoantibodies
• Receptors, Cholinergic

Topics

• Aged
• Autoantibodies (blood, immunology)
• Humans
• Male
• Myasthenia Gravis (blood, diagnosis, immunology)
• Peripheral Nervous System Diseases (blood, diagnosis, immunology)
• Receptors, Cholinergic (biosynthesis, immunology)