Plasma Exchange Did Not Reduce Viral Load in a Recovered Case of Severe Fever with Thrombocytopenia Syndrome.

Abstract

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease caused by the SFTS virus (SFTSV). There is no specific treatment for SFTS, although several reports have indicated that plasma exchange (PE) can be an effective therapy for severe SFTS. However, whether or not PE can reduce the viral load is unclear. We herein report a woman with SFTS who had her SFTSV viral load measured just before and after PE. While the patient recovered, there was no significant difference in the SFTSV viral load after PE. Our results confirmed that PE itself does not reduce the SFTSV viral load.

• Authors: Rie Utsunomiya Nishimizu, Seiji Shiota, Toshihiro Ishii, Kaori Sano, Tadaki Suzuki, Hideki Hasegawa, Eishi Miyazaki
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 61 Issue 2 Pg. 253-256 (Jan 15 2022) ISSN: 1349-7235 [Electronic] Japan
• PMID: 34334561 (Publication Type: Case Reports, Journal Article)

Topics

• Bunyaviridae Infections (therapy)
• Female
• Humans
• Phlebovirus
• Plasma Exchange
• Serologic Tests
• Severe Fever with Thrombocytopenia Syndrome
• Viral Load