Abstract | BACKGROUND: PURPOSE: to evaluate the impact on the menstrual cycles and related endocrine abnormalities in women with VLD and respective roles of liver function and portal hypertension. STUDY DESIGN: This was a single-center observational cohort study. Forty-seven premenopausal women with vascular liver disease were included for endocrine and gynecological assessments. Endocrine evaluation was performed at inclusion. Tolerance of contraception was followed up and assessed at 3 and 12 months. PARTICIPANTS, SETTING, METHODS: RESULTS: CONCLUSION AND IMPLICATIONS: endocrine abnormalities, prior described in association with cirrhosis, are also identified in patients with vascular liver disease, and require specific management. Glucose intolerance profile is frequent, further studies are needed to assess significant consequences on cardio-vascular system.
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Authors | Tatiana Stempak-Droissart, Christine Rousset-Jablonski, Poli M Spritzer, Najiba Lalhou, Etienne Larger, Caroline Pichard, Aurélie Plessier, Anne Gompel |
Journal | Clinics and research in hepatology and gastroenterology
(Clin Res Hepatol Gastroenterol)
Vol. 46
Issue 1
Pg. 101756
(Jan 2022)
ISSN: 2210-741X [Electronic] France |
PMID | 34303004
(Publication Type: Journal Article, Observational Study)
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Copyright | Copyright © 2021 Elsevier Masson SAS. All rights reserved. |
Chemical References |
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Topics |
- Budd-Chiari Syndrome
- Female
- Glucose Intolerance
- Humans
- Hypertension, Portal
- Menstrual Cycle
- Polycystic Ovary Syndrome
- Testosterone
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