Treatment of AIDS-related Kaposi's Sarcoma With Low-dose Radiotherapy - Follow-up on 2,305 Tumours.

Abstract

BACKGROUND/AIM:

We aimed to report our experience obtained by treating AIDS-related Kaposi's sarcoma (KS) with radiotherapy before the era of antiretroviral therapy.

PATIENTS AND METHODS:

This investigation was performed as a quality control of KS patients treated with low-dose radiotherapy at our department. KS patients referred to our section from 1983 up until 1990, were treated three times with radiotherapy (29-50 kV, 2-4 Gy), once every second week.

RESULTS:

Initially, 74 skin KSs were treated three times with 2 Gy, of which 70% were treated successfully. Hereafter, other 2,066 KSs on the skin were treated three times with 4 Gy with a very high success rate of 93%. Additional 165 mucous KSs were treated three times with 4 Gy, of which 91% were treated successfully.

CONCLUSION:

Low-dose radiotherapy is effective for the treatment of many AIDS-related KS patients.

• Authors: Hans Christian Wulf, Ida M Heerfordt
• Journal: Anticancer research (Anticancer Res) Vol. 41 Issue 8 Pg. 3871-3874 (Aug 2021) ISSN: 1791-7530 [Electronic] Greece
• PMID: 34281848 (Publication Type: Journal Article)
• Copyright: Copyright © 2021 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Topics

• AIDS-Related Opportunistic Infections (pathology, radiotherapy)
• Adult
• Aged
• Follow-Up Studies
• Humans
• Male
• Middle Aged
• Neoplasm Recurrence, Local
• Radiotherapy Dosage
• Sarcoma, Kaposi (pathology, radiotherapy)
• Skin Neoplasms (pathology, radiotherapy, virology)