Radiation-Induced Meningioma in a Case of Medulloblastoma Treated 11 Years Ago-Detected on 68Ga-DOTANOC PET/CT.

Abstract

ABSTRACT:

Medulloblastomas, especially the sonic hedgehog subgroup, are treated aggressively with surgery and chemoradiotherapy, as they are associated with high local site recurrence rate and poor overall survival. Radiation-induced meningioma is the most common delayed complication of craniospinal irradiation. This needs to be differentiated from meningeal or ependymal metastases as the later need aggressive management. We report one such rare case, in a patient who completed treatment for medulloblastoma 11 years ago, was in remission, and now presented with dural-based lesions.

• Authors: Indraja D Dev, Ameya D Puranik, Venkatesh Rangarajan, Tejpal Gupta, Nilendu C Purandare, Archi Agrawal, Sneha Shah
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 47 Issue 1 Pg. e108-e110 (Jan 01 2022) ISSN: 1536-0229 [Electronic] United States
• PMID: 34183498 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Chemical References

• 68Ga-DOTANOC
• Organometallic Compounds

Topics

• Cerebellar Neoplasms (radiotherapy)
• Humans
• Medulloblastoma (radiotherapy)
• Meningioma (diagnostic imaging)
• Neoplasms, Radiation-Induced (diagnostic imaging)
• Organometallic Compounds
• Positron Emission Tomography Computed Tomography