Association of Dietary Diabetes Risk Reduction Score With Risk of Cardiovascular Diseases in the Iranian Population: Tehran Lipid and Glucose Study.

Abstract

BACKGROUND:

There are no data available regarding the association of dietary diabetes risk reduction score (DDRRS) and risk of cardiovascular disease (CVD) worldwide. We aimed to investigate the association of the DDRRS with the risk of CVD outcomes in a prospective population-based study.

METHOD:

Individuals without CVD (n=2,195) were recruited from participants of the Tehran Lipid and Glucose Study (2006-2008) and followed for a mean of 6.7 years. The DDRRS was determined on the basis of eight components using a validated 168-item food frequency questionnaire. Cox proportional hazard regression models, adjusted for potential confounders, were used to estimate the hazard ratios and 95% confidence interval (CI) of CVD across quartiles of DDRRS.

RESULTS:

The mean ± standard deviation age of participants (44.8% male) was 38.8±13.0 years at baseline. Median DDRRS for all patients was 23 (intequartile range 20-26). During follow-up, 77 (3.5%) new cases of CVD were identified. After adjustment for confounding variables, including age, sex, body mass index, physical activity, smoking, energy intake, diabetes, and hypertension, no association was found between DDRRS and risk of CVD (odds ratio, 0.70; 95% CI, 0.36-1.37 [p-value for trend=0.351]).

CONCLUSIONS:

The findings of this study showed that higher DDRRS is not associated with risk of CVD events.

• Authors: Golaleh Asghari, Hossein Farhadnejad, Farshad Teymoori, Hadi Emamat, Mohammad Karim Shahrzad, Ali Siamak Habibi-Moeini, Parvin Mirmiran, Fereidoun Azizi
• Journal: Heart, lung & circulation (Heart Lung Circ) Vol. 31 Issue 1 Pg. 101-109 (Jan 2022) ISSN: 1444-2892 [Electronic] Australia
• PMID: 34176740 (Publication Type: Journal Article)
• Copyright: Copyright © 2021 Australian and New Zealand Society of Cardiac and Thoracic Surgeons (ANZSCTS) and the Cardiac Society of Australia and New Zealand (CSANZ). Published by Elsevier B.V. All rights reserved.

Chemical References

• Lipids
• Glucose

Topics

• Adult
• Cardiovascular Diseases (epidemiology, prevention & control)
• Diabetes Mellitus (epidemiology)
• Female
• Glucose
• Humans
• Incidence
• Iran (epidemiology)
• Lipids
• Male
• Middle Aged
• Prospective Studies
• Risk Factors
• Risk Reduction Behavior