Abstract | OBJECTIVES: METHODS: This study involved 14 patients with Dupuytren's disease who underwent treatment with CCH injection. The range of motion of each phalangeal joint was measured before treatment and at 6 months posttreatment. The following assessments were also carried out pre- and posttreatment: the Geriatric Depression Scale Short - Japanese version (GDS-J) to evaluate depressive status, Hand 10 to assess hand health status, and EuroQol-5-dimension-3-level Japanese version to evaluate health-related quality of life. RESULTS: Significant improvements were found in metacarpophalangeal joint extension and proximal interphalangeal joint extension. Significant differences were also found between values before the initiation of CCH injection and those at 6 months posttreatment for the EuroQol index score and the EuroQol Visual Analog Scale (VAS). Significant positive correlations were found between the pre- to posttreatment change in GDS-J scores and for the change in Hand 10 scores. Moreover, a significant negative correlation was found between the change in GDS-J scores and change in EuroQol index scores/EuroQol VAS scores before and at 6 months after CCH injection. CONCLUSIONS: For patients with Dupuytren's disease, CCH therapy directly improved the health-related quality of life. The degree of improvement of depressive status was associated with the degree of improvement of hand health status and health-related quality of life.
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Authors | Takuro Kuboi, Tsuyoshi Tajika, Fumitaka Endo, Wataru Goto, Ichiro Nakajima, Satoshi Hasegawa, Daisuke Nakajima, Takafumi Hasokawa, Hirotaka Chikuda |
Journal | Progress in rehabilitation medicine
(Prog Rehabil Med)
Vol. 6
Pg. 20210023
( 2021)
ISSN: 2432-1354 [Electronic] Japan |
PMID | 34056142
(Publication Type: Journal Article)
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Copyright | ©2021 The Japanese Association of Rehabilitation Medicine. |