Plant-derived peptides improving lipid and glucose metabolism.

Abstract

Plant protein-derived peptides, focusing especially on soybean protein-derived peptides have considerable effects on metabolic regulation and modulation such as cholesterol lowering, triglyceride lowering, anti-obesity, inhibition of fatty acid synthase, and antidiabetic effects. The molecules targeted to study the metabolic regulatory functions of the peptides included the following: intestinal cholesterol micelle, cholesterol metabolism-related genes for cholesterol lowering, triglyceride metabolism-related genes for triglyceride lowering and anti-obesity, dipeptidyl peptidase-IV (DPP-IV), α-amylase, α-glucosidase, or glucose metabolism-related genes for lowering blood glucose levels. This review article outlines the physiological functions of plant protein-derived peptides for the improvement of lipid and glucose metabolism in vitro or in vivo.

• Authors: Satoshi Nagaoka, Asahi Takeuchi, Arata Banno
• Journal: Peptides (Peptides) Vol. 142 Pg. 170577 (08 2021) ISSN: 1873-5169 [Electronic] United States
• PMID: 34033874 (Publication Type: Journal Article, Review)
• Copyright: Copyright © 2021 Elsevier Inc. All rights reserved.

Chemical References

• Peptide Fragments
• Plant Proteins
• Glucose

Topics

• Glucose (metabolism)
• Lipid Metabolism (drug effects)
• Peptide Fragments (pharmacology)
• Plant Proteins (chemistry, metabolism)