Prenatal management of fetal goiter alternating between hypothyroidism and hyperthyroidism in a mother with Graves' disease.

Abstract

We present a rare documented case with consecutive hypo- and hyperthyroidism during fetal life. First, hypothyroidism was due to transplacental passage of antithyroid drugs. After the mother's thyroidectomy, fetal hyperthyroidism was due to transplacental passage of persistent anti-thyrotropin receptor antibodies. Fetal goiter disappeared after adjusting maternal treatment.

• Authors: Hortense Didier-Mathon, Hanane Bouchghoul, Marie-Victoire Senat, Jacques Young, Dominique Luton
• Journal: Clinical case reports (Clin Case Rep) Vol. 9 Issue 4 Pg. 2281-2284 (Apr 2021) ISSN: 2050-0904 [Print] England
• PMID: 33936679 (Publication Type: Case Reports)
• Copyright: © 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.