Immunoglobulin G4-Related Disease Masquerading an Epidural Spinal Cord Tumor.

Abstract

Background  Immunoglobulin G4-related disease (IgG4-RD) is a recently identified multisystemic fibroinflammatory condition of unclear etiology. IgG4-RD of the epidural tissue causing spinal cord compression is extremely rare. Case description  Here, we present a 27-year-old male with epidural mass, causing spinal cord compression at the level of D5-D6. The mass proved pathologically to be epidural inflammatory pseudotumor (IPT) related to IgG4. Spinal decompression was done. The patient was started on steroid treatment and reported a complete resolution of his symptoms over a 3 years' follow-up period. Conclusion  To the authors' knowledge, this is the first case of IgG4-related epidural IPT and spinal cord compression in Bahrain and the Middle East. IgG4-RD should always be considered as a part of the differential diagnosis of spinal tumors.

• Authors: Ebtesam Abdulla, Harleen Luther, Tejal Shah, Nisha Chandran
• Journal: Journal of neurosciences in rural practice (J Neurosci Rural Pract) Vol. 12 Issue 2 Pg. 424-426 (Apr 2021) ISSN: 0976-3147 [Print] United States
• PMID: 33927535 (Publication Type: Case Reports)
• Copyright: Association for Helping Neurosurgical Sick People. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).