Tannic acid-based metal phenolic networks for bio-applications: a review.

Abstract

Tannic acid (TA), a large polyphenolic molecule, has long been known for use in food additives, antioxidants, bio-sorbents, animal feed and adhesives due to its intrinsic properties such as antioxidation, metal chelation, and polymerization. Recently, there has been a renewed interest in fabricating engineered advanced materials with TA modification for novel bio-applications. The modification process involves various interactions/reactions based on its diverse chemical structure, contributed by abundant aromatic rings and hydroxyl groups. In addition, the obtained composites are endowed with retained TA activity and novel enhanced properties. Therefore, the aim of this review is to highlight the recent biomedical application of TA-based metal phenolic networks (TA-MPNs) by focusing on their intrinsic properties and the endowed ability for novel engineered functional composites. The potential contributions of TA-MPNs in "Tumor Theranostics", "Anti-Bacterial Ability", "Wound Repair for Skin Regeneration" and "Bone Tissue Regeneration Applications" are summarized in this paper.

• Authors: Zhenhu Guo, Wensheng Xie, Jingsong Lu, Xiaoxiao Guo, Jianzhong Xu, Wanling Xu, Yongjie Chi, Nonaka Takuya, Hong Wu, Lingyun Zhao
• Journal: Journal of materials chemistry. B (J Mater Chem B) Vol. 9 Issue 20 Pg. 4098-4110 (05 26 2021) ISSN: 2050-7518 [Electronic] England
• PMID: 33913461 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Anti-Bacterial Agents
• Antineoplastic Agents
• Coordination Complexes
• Tannins

Topics

• Anti-Bacterial Agents (chemistry, pharmacology)
• Antineoplastic Agents (chemistry, pharmacology)
• Bacteria (drug effects)
• Coordination Complexes (chemistry, pharmacology)
• Humans
• Neoplasms (drug therapy)
• Tannins (chemistry, pharmacology)
• Theranostic Nanomedicine