Abstract |
Basal cell carcinoma (BCC) can be a component of a collision tumor in which the skin cancer is present at the same cutaneous site as either a benign tumor or a malignant neoplasm. However, BCC can also concurrently occur at the same skin location as a non-neoplastic cutaneous condition. These include autoimmune diseases ( vitiligo), cutaneous disorders ( Darier disease), dermal conditions ( granuloma faciale), dermal depositions ( amyloid, calcinosis cutis, cutaneous focal mucinosis, osteoma cutis, and tattoo), dermatitis, miscellaneous conditions ( rhinophyma, sarcoidal reaction, and varicose veins), scars, surgical sites, systemic diseases ( sarcoidosis), systemic infections (leischmaniasis, leprosy and lupus vulgaris), and ulcers. The relationship between the BCC and the coexisting non-neoplastic condition may be coincidental or possibly related to the development of the BCC; alternatively, the development of the BCC may be unrelated to the coexisting non-neoplastic conditions and secondary to either a Koebner isomorphic response or a Wolf isotopic response in an immunocompromised district of skin. This paper reviews several of the case reports and studies that describe the association of BCC with these non-neoplastic cutaneous conditions.
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Authors | Philip R Cohen |
Journal | Dermatology online journal
(Dermatol Online J)
Vol. 27
Issue 2
(Feb 15 2021)
ISSN: 1087-2108 [Electronic] United States |
PMID | 33818975
(Publication Type: Journal Article, Review)
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Topics |
- Carcinoma, Basal Cell
(complications)
- Humans
- Skin Diseases
(complications)
- Skin Neoplasms
(complications)
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