Case Report: Early Breast Cancer Recurrence Mimicking BIA-ALCL in a Patient With Multiple Breast Procedures.

Abstract

Breast reconstruction plays a fundamental role in the therapeutic process of breast cancer treatment and breast implants represents the leading breast reconstruction strategy. Breast Implant Associated-Anaplastic Large Cell Lymphoma (BIA-ALCL), locoregional recurrence in the skin flap, and skin flap necrosis are well-known complications following mastectomy and immediate breast reconstruction (IBR). We report a case of locoregional cancer recurrence in the mastectomy flap mimicking BIA-ALCL, in a patient who underwent 6 breast procedures in four facilities across 15 years including immediate breast reconstruction with macrotextured breast implants. Despite the rate and onset of the disease, clinicians should be aware of BIA-ALCL. Due to the risk of false negative results of fine needle aspiration, clinical suspicion of BIA-ALCL should drive clinicians' choices, aside from cytological results. In the present case, surgical capsulectomy of the abnormal periprosthesic tissue revealed locoregional recurrence.

• Authors: Marco Materazzo, Gianluca Vanni, Marco Pellicciaro, Lucia Anemona, Francesca Servadei, Erika Giacobbi, Andrea Farinaccio, Chiara Adriana Pistolese, Tommaso Perretta, Marcello Chiocchi, Valentina Bruno, Federico Tacconi, Amir Sadri, Adriano De Majo, Camilla Di Pasquali, Rosaria Meucci, Francesca Santori, Maria Cotesta, Oreste Claudio Buonomo
• Journal: Frontiers in surgery (Front Surg) Vol. 8 Pg. 606864 ( 2021) ISSN: 2296-875X [Print] Switzerland
• PMID: 33768110 (Publication Type: Case Reports)
• Copyright: Copyright © 2021 Materazzo, Vanni, Pellicciaro, Anemona, Servadei, Giacobbi, Farinaccio, Pistolese, Perretta, Chiocchi, Bruno, Tacconi, Sadri, De Majo, Di Pasquali, Meucci, Santori, Cotesta and Buonomo.