Indicators of antioxidant protection of blood in necrotizing ulcerative gingivitis in experimental animals.

Abstract

This article highlights the results of a study of blood parameters in animals with simulated necrotizing ulcerative gingivitis and compares them, under the same conditions, with animals that received local treatment with a developed complex of antioxidant drugs. Following the work tasks, the nature of changes in the state of the antioxidant - prooxidant system and their influence on quantitative and functional indicators of markers of inflammatory intensity was analyzed and investigated during the pathological process in the background and without treatment with a developed complex. This work shows the changes of malonic dialdehyde concentration as an indicator of lipid peroxidation intensity in experimental animals, the level of catalase activity in the blood of animals, and antioxidant-prooxidant balance in the dynamics of necrotizing ulcerative gingivitis.

• Authors: Yuliia Hafizivna Kilmukhametova, Viktor Markiyanovich Batig, Marianna Alexandrovna Ostafiichuk, Olha Mykhaylivna Tokar, Tatiana Anatoliyivna Glushchenko, Iryna Viktorivna Batih, Michael Ivanovich Sheremet
• Journal: Journal of medicine and life (J Med Life) 2021 Jan-Mar Vol. 14 Issue 1 Pg. 68-74 ISSN: 1844-3117 [Electronic] Romania
• PMID: 33767788 (Publication Type: Journal Article)
• Copyright: ©2020 JOURNAL of MEDICINE and LIFE.

Chemical References

• Antioxidants
• Biomarkers
• Reactive Oxygen Species
• Malondialdehyde
• Catalase

Topics

• Animals
• Antioxidants (metabolism)
• Biomarkers (blood)
• Catalase (blood)
• Gingivitis, Necrotizing Ulcerative (blood)
• Humans
• Lipid Peroxidation
• Male
• Malondialdehyde (blood)
• Oxidation-Reduction
• Rabbits
• Reactive Oxygen Species (blood)