Endovascular and medical therapy of May-Thurner syndrome: Case series and scoping literature review.

Abstract

INTRODUCTION:

May-Thurner syndrome has been recognized as a cause of chronic venous insufficiency and a trigger for venous thromboembolism. There is no consensus about the definition, diagnosis, and therapeutic approach. We are aiming to describe its characteristics and a scoping literature review.

METHODS:

A retrospective review of patients with May-Thurner syndrome from March 2010 to May 2018 and scoping literature review were made.

RESULTS:

Seven patients were identified. All patients were female with a median age of 36 (20-60) years. The median time from the first symptom to diagnosis was 3.41 (0.01-9) years. The primary clinical presentation was post-thrombotic syndrome (4 patients). Six patients had at least one risk factor for deep venous thrombosis. All patients underwent angioplasty with stent; patients with acute deep venous thrombosis, furthermore mechanic thrombectomy with or without catheter-directed thrombolysis were done. There were three complications (one patient, lymphedema, and two venous stent thrombosis). Scoping review results were descriptively summarized.

CONCLUSION:

May-Thurner syndrome has a varied spectrum of clinical presentation, and clinical awareness is paramount for diagnosis. Its principal complication is the post-thrombotic syndrome, which is associated with high morbidity. There is no consensus on the antithrombotic treatment approach.

• Authors: M C Montes, J P Carbonell, J E Gómez-Mesa
• Journal: Journal de medecine vasculaire (J Med Vasc) Vol. 46 Issue 2 Pg. 80-89 (Apr 2021) ISSN: 2542-4513 [Print] France
• PMID: 33752850 (Publication Type: Journal Article, Review)
• Copyright: Copyright © 2021 Elsevier Masson SAS. All rights reserved.

Topics

• Adult
• Angioplasty (adverse effects, instrumentation)
• Female
• Humans
• Male
• May-Thurner Syndrome (complications, diagnostic imaging, therapy)
• Middle Aged
• Postthrombotic Syndrome (diagnosis, etiology, therapy)
• Recurrence
• Retrospective Studies
• Stents
• Thrombectomy (adverse effects)
• Thrombolytic Therapy (adverse effects)
• Treatment Outcome
• Venous Thrombosis (diagnostic imaging, etiology, therapy)
• Young Adult