Pathogen Effectors: Exploiting the Promiscuity of Plant Signaling Hubs.

Abstract

Pathogens produce effectors to overcome plant immunity, thereby threatening crop yields and global food security. Large-scale interactomic studies have revealed that pathogens from different kingdoms of life target common plant proteins during infection, the so-called effector hubs. These hubs often play central roles in numerous plant processes through their ability to interact with multiple plant proteins. This ability arises partly from the presence of intrinsically disordered domains (IDDs) in their structure. Here, we highlight the role of the TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR (TCP) and JASMONATE-ZIM DOMAIN (JAZ) transcription regulator families as plant signaling and effector hubs. We consider different evolutionary hypotheses to rationalize the existence of diverse effectors sharing common targets and the possible role of IDDs in this interaction.

• Authors: Evi Ceulemans, Heba M M Ibrahim, Barbara De Coninck, Alain Goossens
• Journal: Trends in plant science (Trends Plant Sci) Vol. 26 Issue 8 Pg. 780-795 (08 2021) ISSN: 1878-4372 [Electronic] England
• PMID: 33674173 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
• Copyright: Copyright © 2021 Elsevier Ltd. All rights reserved.

Chemical References

• Plant Proteins

Topics

• Gene Expression Regulation, Plant
• Plant Immunity (genetics)
• Plant Proteins (genetics)
• Plants (genetics)
• Signal Transduction