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Treatment of the premenstrual syndrome.

Abstract
A placebo-controlled, randomized, double-blind, parallel group study in hospital and general practice has shown that a combination of belladonna alkaloids, ergotamine tartrate, and phenobarbitone (Bellergal) was effective in treating troublesome symptoms of the premenstrual syndrome of which fatigue, tender breasts, nervousness, irritability, lethargy and listlessness were improved to a statistically significant degree. The drug was given three times daily and caused no side effects.
AuthorsK Robinson, K M Huntington, M G Wallace
JournalBritish journal of obstetrics and gynaecology (Br J Obstet Gynaecol) Vol. 84 Issue 10 Pg. 784-8 (Oct 1977) ISSN: 0306-5456 [Print] England
PMID336078 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Belladonna Alkaloids
  • Drug Combinations
  • Ergotamine
  • Phenobarbital
Topics
  • Adolescent
  • Adult
  • Belladonna Alkaloids (therapeutic use)
  • Clinical Trials as Topic
  • Drug Combinations
  • Ergotamine (therapeutic use)
  • Female
  • Humans
  • Middle Aged
  • Phenobarbital (therapeutic use)
  • Premenstrual Syndrome (drug therapy)

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