Abstract | AIMS: METHODS: This retrospective, observational study used data from Optum. The T2D-CAD cohort (n = 154,369) included patients (≥50 years old) either with high cardiovascular risk or taking a P2Y12 inhibitor. The THEMIS-like cohort (n = 126,938) comprised patients (≥50 years old) at high cardiovascular risk; the THEMIS-PCI-like cohort comprised a subset of these patients with prior percutaneous coronary intervention (PCI) (n = 18,394). RESULTS: Mean follow-up was 2.4-2.5 years. Incidence rates of the composite outcome (death, MI, and stroke) were 6.56 (95% CI 6.50-6.63), 6.21 (6.14-6.28), and 5.57 (5.39-5.74) per 100 person-years, and annualized healthcare costs per patient were US$15,848, US$16,044, and US$20,934 for the T2D-CAD, THEMIS-like, and THEMIS-PCI-like cohorts, respectively. CONCLUSIONS: Commercially insured patients similar to those in THEMIS had high cardiovascular event rates and healthcare costs, highlighting a need for improved preventive strategies.
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Authors | Eric Wittbrodt, Narinder Bhalla, Karolina Andersson Sundell, Phillip Hunt, Nathan D Wong, Marco Kuster, Carl Mellström |
Journal | Journal of diabetes and its complications
(J Diabetes Complications)
Vol. 35
Issue 4
Pg. 107859
(04 2021)
ISSN: 1873-460X [Electronic] United States |
PMID | 33558152
(Publication Type: Journal Article, Observational Study, Research Support, Non-U.S. Gov't)
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Copyright | Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved. |
Chemical References |
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Topics |
- Aspirin
(therapeutic use)
- Coronary Artery Disease
- Cost of Illness
- Delivery of Health Care
- Diabetes Mellitus, Type 2
(complications, drug therapy, epidemiology)
- Humans
- Middle Aged
- Myocardial Infarction
(epidemiology)
- Percutaneous Coronary Intervention
- Retrospective Studies
- Risk Factors
- Stroke
(epidemiology, etiology, prevention & control)
- Treatment Outcome
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