RESULTS: There were 394 male patients (69%) and 180 female patients (31%). After adjusting for baseline differences, propensity score matching compared 171 male patients with 171 female patients. No difference was seen between men and women in in-hospital mortality (60.2% vs 56.7%; P = .59), limb
ischemia (47.4% vs 45.6%; P = .83), limb
ischemia surgery (15.2% vs 12.9%; P = .64),
bleeding (49.7% vs 49.1%; P = 1),
continuous venovenous hemofiltration initiation (39.2% vs 32.7%; P = .26), and
stroke (8.2% vs 9.4%; P = .85). Multivariable logistic regression showed that female patients who died were more likely to have had
chronic kidney disease (odds ratio [OR], 2.67; 95% confidence interval [CI], 1.09-6.53; P = .032) than surviving women. Male patients who died were more likely to have had
coronary artery disease (OR, 2.25; 95% CI, 1.34-3.78; P = .002) and higher
lactate levels (OR, 1.14; 95% CI, 1.08-1.21; P < .001) than surviving men. Women with cardiac transplant
primary graft dysfunction were more likely to survive (OR, 0.04; 95% CI, 0.01-0.27; P = .001), whereas men with cardiac transplant
primary graft dysfunction were less likely to survive (OR, 0.28; 95% CI, 0.11-0.71; P = .007), than patients with other
shock etiologies.
CONCLUSIONS: After adjusting for baseline difference, there was no difference in outcomes between male and female patients despite differing risk profiles for in-hospital mortality.