Acute suppurative thyroiditis account for <1% of
thyroid diseases and is uncommon because of the gland's encapsulation,
iodine-rich environment, good vascular supply and extensive lymphatic drainage. It has been reported in patients with underlying
goiters,
thyroid cancers and in immuno-compromised patients. The usual causative organisms are Staphylococci spp. and Streptococci spp. Rarer organisms include Klebsiella spp. and Salmonella spp. Due to its rarity (as there have been only 28 cases of Salmonella thyroid
abscess being reported in the literature till 2020), only case reports are available to guide management. We report two cases of thyroid
abscess due to Salmonella enteritidis in our institution that may herald the re-emergence of this uncommon
infection of the thyroid gland and to raise awareness for all clinicians. Both patients presented with neck swelling,
dysphagia and
sepsis. Surgical intervention was warranted in both patients due to the severity of the disease and failed medical
therapy. Recovery was uneventful following adequate surgical intervention and
antibiotic therapy according to the culture and sensitivity report of the pathogen. This case report highlights that both patients were immunocompromised, and they contracted Salmonella thyroid
abscess without any gastrointestinal involvement. Thus, a high index of suspicion for Salmonella thyroid
abscess in immunocompromised patients can expedite the diagnosis and appropriate management can be commenced such as
antibiotic therapy, percutaneous aspiration and surgical drainage in the event of failed medical
therapy.