Abstract | OBJECTIVES: METHODS: Two hundred ninety-five patients who underwent coronary artery bypass grafting using Y-composite grafts based on the in situ left internal thoracic artery, and in whom preoperative stress/rest myocardial single-photon-emission computed tomography and 1-year angiographies were available were enrolled. Seven hundred sixty-nine and 262 distal anastomoses were constructed to ischemic and nonischemic areas, respectively. One-year and 5-year angiographic occlusion rates were evaluated in all and 80.3% of study patients, respectively. Factors associated with graft occlusion were evaluated using generalized linear mixed-effects models. RESULTS: Overall 1- and 5-year graft occlusion rates were 4.3% (44 of 1031 distal anastomoses) and 5.5% (45 out of 820), respectively. The occlusion rates of grafts bypassed to vessels with functionally significant and insignificant stenosis were 2.7% (21 out of 769) and 8.8% (23 out of 262) at 1 year and were 4.0% (25 out of 618) and 9.9% (20 out of 202) at 5 years, respectively. Graft occlusion during the 5 years after coronary artery bypass grafting was associated with the functional significance of coronary artery stenosis (odds ratio, 0.50; 95% confidence interval, 0.28-0.92). The odds ratio of the graft occlusion according to functional ischemia was lower and significant in grafts to arteries with intermediate stenosis ( stenosis ≥70% but <90%; odds ratio, 0.34; 95% confidence interval, 0.13-0.93) whereas it was higher and insignificant in grafts to arteries with severe stenosis (≥90% stenosis; odds ratio, 0.76; 95% confidence interval, 0.33-1.72). CONCLUSIONS:
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Authors | Ho Young Hwang, Jin Chul Paeng, Jeehoon Kang, Myoung-Jin Jang, Ki-Bong Kim |
Journal | The Journal of thoracic and cardiovascular surgery
(J Thorac Cardiovasc Surg)
Vol. 161
Issue 3
Pg. 1010-1018.e1
(Mar 2021)
ISSN: 1097-685X [Electronic] United States |
PMID | 33431208
(Publication Type: Journal Article, Observational Study, Webcast)
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Copyright | Copyright © 2020 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved. |
Topics |
- Aged
- Coronary Angiography
- Coronary Artery Bypass
(adverse effects)
- Coronary Circulation
- Coronary Stenosis
(diagnostic imaging, physiopathology, surgery)
- Female
- Graft Occlusion, Vascular
(diagnostic imaging, etiology, physiopathology)
- Humans
- Male
- Middle Aged
- Myocardial Perfusion Imaging
- Predictive Value of Tests
- Retrospective Studies
- Risk Assessment
- Risk Factors
- Severity of Illness Index
- Time Factors
- Tomography, Emission-Computed, Single-Photon
- Treatment Outcome
- Vascular Patency
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