Beta-Blockade in Intraseptal Anomalous Coronary Artery With Reversible Myocardial Ischemia.

Abstract

Anomalous aortic origin of a left coronary artery (L-AAOCA) with an intraseptal course is a rare anomaly and can be associated with myocardial ischemia and sudden cardiac death. No surgical or medical intervention is known to improve patient outcomes. A 7-year-old boy with intraseptal L-AAOCA presented with nonexertional chest pain, syncope, and had reversible myocardial ischemia on provocative testing. The patient was started on β-blockade, following which his symptoms improved and resolved over a period of six years. A follow-up dobutamine stress magnetic resonance imaging no longer showed reversible ischemia, and cardiac catheterization with fractional flow reserve did not show coronary flow compromise.

• Authors: Tam T Doan, Athar M Qureshi, Shagun Sachdeva, Cory V Noel, Dana Reaves-O'Neal, Silvana Molossi
• Journal: World journal for pediatric & congenital heart surgery (World J Pediatr Congenit Heart Surg) Vol. 12 Issue 1 Pg. 145-148 (Jan 2021) ISSN: 2150-136X [Electronic] United States
• PMID: 33407035 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adrenergic beta-Antagonists

Topics

• Adrenergic beta-Antagonists (therapeutic use)
• Cardiac Catheterization
• Child
• Coronary Angiography
• Coronary Sinus (abnormalities)
• Coronary Vessel Anomalies (complications, diagnosis, therapy)
• Electrocardiography
• Fractional Flow Reserve, Myocardial (physiology)
• Humans
• Magnetic Resonance Imaging, Cine
• Male
• Myocardial Ischemia (diagnosis, etiology, therapy)
• Vascular Surgical Procedures (methods)