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[Medication rules of traditional Chinese medicine for the treatment of premature ejaculation: An analysis based on data mining].

AbstractOBJECTIVE:
To study the medication rules of traditional Chinese medicine (TCM) in the treatment of premature ejaculation.
METHODS:
We searched the databases of CNKI, Wan Fang, VIP, SinoMed (CBM) and PubMed for studies on the treatment of PE with TCM prescriptions and performed statistical analyses on the data obtained using the TCM inheritance auxiliary platform software.
RESULTS:
Totally 180 prescriptions were identified, involving 209 TCM drugs. The results of statistical analysis showed that the TCM drugs for the treatment of premature ejaculation were mostly warm, flat or cold in nature, sweet or spicy in taste, and with the kidney, liver and spleen meridian tropisms. The single TCM drugs most commonly used included Lycium barbarum L (Gouqizi), followed by Epimedium brevicornum Maxim (Yinyanghuo), Os draconis (Longgu), Fructus rosae laevigatae (Jinyingzi), and the drugs most frequently used in combination with others in a prescription were Os draconis (Longgu) and Concha ostreae (Muli). Seven newly derived prescriptions were identified in addition.
CONCLUSIONS:
The compatibility of TCM in the treatment of premature ejaculation is characterized by the combination of the drugs for tonifying the kidney and arresting seminal emission as the main medication strategy, with those for soothing the liver and invigorating the spleen as the adjuvant agents, which has a certain clinical application value.
AuthorsYan Liu, Li-Ting Yang, Wen-Jie Long, Ling-Jun Wang, Zhao-Hui Wang
JournalZhonghua nan ke xue = National journal of andrology (Zhonghua Nan Ke Xue) Vol. 26 Issue 7 Pg. 650-655 (Jul 2020) ISSN: 1009-3591 [Print] China
PMID33377723 (Publication Type: Journal Article)
Chemical References
  • Drugs, Chinese Herbal
Topics
  • Data Mining
  • Drugs, Chinese Herbal (therapeutic use)
  • Humans
  • Medicine, Chinese Traditional
  • Meridians
  • Premature Ejaculation (drug therapy)

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