Abstract | CONTEXT: This review presents an up-to-date summary on management of type 1 diabetes mellitus (T1DM) among women of reproductive age and covers the following time periods: preconception, gestation, and postpartum. EVIDENCE ACQUISITION: A systematic search and review of the literature for randomized controlled trials and other studies evaluating management of T1DM before pregnancy, during pregnancy, and postpartum was performed. EVIDENCE SYNTHESIS: Preconception planning should begin early in the reproductive years for young women with T1DM. Preconception and during pregnancy, it is recommended to have near-normal glucose values to prevent adverse maternal and neonatal outcomes, including fetal demise, congenital anomaly, pre-eclampsia, macrosomia, neonatal respiratory distress, neonatal hyperbilirubinemia, and neonatal hypoglycemia. CONCLUSION: Women with T1DM can have healthy, safe pregnancies with preconception planning, optimal glycemic control, and multidisciplinary care.
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Authors | Elizabeth O Buschur, Sarit Polsky |
Journal | The Journal of clinical endocrinology and metabolism
(J Clin Endocrinol Metab)
Vol. 106
Issue 4
Pg. 952-967
(03 25 2021)
ISSN: 1945-7197 [Electronic] United States |
PMID | 33331893
(Publication Type: Journal Article, Systematic Review)
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Copyright | © The Author(s) 2020. Published by Oxford University Press on behalf of the Endocrine Society. All rights reserved. For permissions, please e-mail: [email protected]. |
Topics |
- Adult
- Diabetes Mellitus, Type 1
(epidemiology, therapy)
- Female
- Humans
- Infant, Newborn
- Postnatal Care
(methods, standards)
- Postpartum Period
(physiology)
- Preconception Care
(methods, standards)
- Pregnancy
- Pregnancy Outcome
(epidemiology)
- Pregnancy in Diabetics
(epidemiology, therapy)
- Prenatal Care
(methods, standards)
- Young Adult
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