Abstract | BACKGROUND: Advances in ECMO have made it a useful adjunct in critically ill pediatric patients; however, a dearth of evidence exists regarding risks and benefits in pediatric abdominal transplantation. The purpose of this study was to perform a qualitative systematic review of outcomes in pediatric patients undergoing ECMO support pre- or post-abdominal organ transplantation. METHODS: This was a systematic review conducted from Jan 1, 1989, to April 24, 2020, via PubMed, Embase, Scopus, Web of Science, the Cochrane Library, and ClinicalTrials.gov of all pediatric solid abdominal organ transplant recipients (pre- and post-transplant) and donors who underwent V-A or V-V ECMO cannulation. Death was the primary outcome, with graft function and complications as secondary outcomes. RESULTS: CONCLUSIONS: The data are poor on ECMO usage in pediatric abdominal transplantation. While complications were high, mortality did not appear to be related to ECMO usage and was relatively low given the severity of patient illness.
|
Authors | Trista D Reid, Ian Kratzke, Diana Dayal, Lauren Raff, Aman Kumar, Michael R Phillips, Rebecca Carlson, Chirag S Desai |
Journal | Pediatric transplantation
(Pediatr Transplant)
Vol. 25
Issue 3
Pg. e13939
(May 2021)
ISSN: 1399-3046 [Electronic] Denmark |
PMID | 33314532
(Publication Type: Journal Article, Systematic Review)
|
Copyright | © 2020 Wiley Periodicals LLC. |
Topics |
- Adolescent
- Child
- Child, Preschool
- Extracorporeal Membrane Oxygenation
- Humans
- Infant
- Liver Transplantation
- Perioperative Care
- Qualitative Research
|