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RB1 loss induced small cell lung cancer transformation as acquired resistance to pembrolizumab in an advanced NSCLC patient.

AuthorsSayaka Arakawa, Tatsuya Yoshida, Masayuki Shirasawa, Daisuke Takayanagi, Shigehiro Yagishita, Noriko Motoi, Yuichiro Ohe
JournalLung cancer (Amsterdam, Netherlands) (Lung Cancer) Vol. 151 Pg. 101-103 (01 2021) ISSN: 1872-8332 [Electronic] Ireland
PMID33279272 (Publication Type: Letter)
Chemical References
  • Antibodies, Monoclonal, Humanized
  • RB1 protein, human
  • Retinoblastoma Binding Proteins
  • pembrolizumab
  • Ubiquitin-Protein Ligases
Topics
  • Antibodies, Monoclonal, Humanized (pharmacology, therapeutic use)
  • Carcinoma, Non-Small-Cell Lung (drug therapy)
  • Drug Resistance, Neoplasm
  • Humans
  • Lung Neoplasms (drug therapy)
  • Retinoblastoma Binding Proteins (genetics)
  • Small Cell Lung Carcinoma
  • Ubiquitin-Protein Ligases (genetics)

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