Comparison of 3D T1-SPACE and DSA in evaluation of intracranial in-stent restenosis.

Abstract

OBJECTIVE:

In-stent restenosis (ISR) after stenting for intracranial stenosis is a significant issue. This study aimed to evaluate the usefulness of the 3D T1-SPACE technique in the follow-up of patients after stent implantation.

METHODS:

Fifteen patients with intracranial arterial stenosis were prospectively enrolled 6-8 months after stenting. Digital subtraction angiography (DSA) and 3D T1-SPACE imaging were performed to evaluate the degree of stenosis and the enhancement of the vessel wall. Bland-Altman plots were used to assess the agreement between the two imaging methods, and the Pearson correlation coefficient was calculated as a measure of the linear correlation.

RESULTS:

Eight Enterprise stents and seven Wingspan stents were used in 15 patients. The follow-up DSA after 6-8 months showed that the degree of stenosis was 40% (range, 30-72%), and ISR occurred in 4 of 15 (26.7%) lesions. The degree of stenosis assessed using the 3D T1-SPACE imaging technique was 35% (range, 30-75%). All four patients with ISR demonstrated significant enhancement. The Pearson correlation coefficient between the two methods was 0.959 (p < 0.05), and the Bland-Altman plot showed that all data points were within the consistency limits ([Formula: see text] ± 1.96 s).

CONCLUSION:

As a non-invasive imaging modality, 3D T1-SPACE showed great consistency with DSA in measuring the degree of stenosis after intracranial stenting. It may be used as an optional method for detecting ISR.

ADVANCES IN KNOWLEDGE:

This study evaluated the usefulness of 3D T1-SPACE technique in the follow-up of patients after stent implantation, which could be used as an optional and non-invasive method in detection of in-stent restenosis.

• Authors: Qiuji Shao, Qiang Li, Qiaowei Wu, Tianxiao Li, Li Li, Kaitao Chang
• Journal: The British journal of radiology (Br J Radiol) Vol. 94 Issue 1118 Pg. 20190950 (Feb 01 2021) ISSN: 1748-880X [Electronic] England
• PMID: 33259233 (Publication Type: Comparative Study, Journal Article)

Topics

• Adult
• Aged
• Angiography, Digital Subtraction (methods)
• Arteries (diagnostic imaging)
• Cerebral Angiography (methods)
• Female
• Follow-Up Studies
• Graft Occlusion, Vascular (diagnostic imaging)
• Humans
• Imaging, Three-Dimensional (methods)
• Intracranial Arteriosclerosis (diagnostic imaging)
• Magnetic Resonance Imaging (methods)
• Male
• Middle Aged
• Prospective Studies