Abstract | OBJECTIVE: METHODS: One hundred migraine patients and 46 healthy subjects were recruited. Patients were randomized into the acupuncture, sham acupuncture, and waiting list groups. Resting-state functional magnetic resonance imaging data were collected at baseline and after 1 month of longitudinal acupuncture treatments. Fractional amplitude of low-frequency fluctuations (fALFF) calculations were applied to explore the associations between baseline fALFF and changes in clinical variables in the acupuncture treatment group and the waiting list group. RESULTS: Compared with healthy subjects, migraine patients had lower fALFF in the left rostral ventromedial medulla, right thalamus, left amygdala, and right angular gyrus. Regression analyses revealed that baseline fALFF values in the left middle frontal gyrus, left superior temporal gyrus, and middle temporal gyrus were positively associated with headache intensity changes in the acupuncture treatment group, while baseline fALFF values in the bilateral lingual gyrus and cuneus were negatively associated with headache intensity changes in this group. CONCLUSION:
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Authors | Zhengjie Li, Jun Zhou, Shirui Cheng, Lei Lan, Ruirui Sun, Mailan Liu, Jie Yang, Yujie Gao, Taipin Guo, Qiyong Gong, Fang Zeng, Fanrong Liang |
Journal | Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
(J Tradit Chin Med)
Vol. 40
Issue 6
Pg. 1041-1051
(12 2020)
ISSN: 2589-451X [Electronic] China |
PMID | 33258357
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Topics |
- Acupuncture Therapy
- Adult
- Brain
(diagnostic imaging)
- Female
- Headache
(diagnostic imaging, therapy)
- Humans
- Magnetic Resonance Imaging
- Male
- Migraine Disorders
(diagnostic imaging, therapy)
- Treatment Outcome
- Young Adult
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