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Effect of fusaric acid on tardive dyskinesia and mental state in psychogeriatric patients. A pilot study.

Abstract
The effect of fusaric acid 150-450 mg daily on tardive dyskinesia and mental state was studied in 15 chronic psychogeriatric patients. The patient's previous drug treatment was maintained unchanged during the experiment. Fusaric acid significantly relieved oro-facial dyskinesia, tremor, and rigidity, and it improved the mental state of the patients (BPRS). Akathisia was exacerbated, but this change was not significant. Akinesia and anxiety were not altered.
AuthorsM Viukari, M Linnoila
JournalActa psychiatrica Scandinavica (Acta Psychiatr Scand) Vol. 56 Issue 1 Pg. 57-61 (Jul 1977) ISSN: 0001-690X [Print] United States
PMID331875 (Publication Type: Clinical Trial, Journal Article)
Chemical References
  • Picolinic Acids
  • Fusaric Acid
Topics
  • Aged
  • Clinical Trials as Topic
  • Drug Evaluation
  • Dyskinesia, Drug-Induced (drug therapy)
  • Fusaric Acid (adverse effects, pharmacology, therapeutic use)
  • Humans
  • Mental Processes (drug effects)
  • Picolinic Acids (therapeutic use)
  • Pilot Projects

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