5-aminolevulinic acid fluorescence guided surgery for resection of cystic meningioma with bone invasion.

Abstract

Meningiomas have a 5 year recurrence rate of 8%. Histological grade and extent of resection are the two main prognostic factors. Cystic meningiomas represent between 2 and 4% of meningiomas, and the complete resection rate in these cases is 62.7%. 5-ALA has been shown to be useful in detecting tumour remnants that could go unnoticed by the conventional microsurgical technique, thereby achieving more complete resections. We present the case of a 66-year-old patient with a frontal convexity meningioma, presenting with a cystic component and bone invasion, who was treated using 5-ALA fluorescence-guided surgery. Fluorescence emission from the tumour tissue allowed the areas of bone invasion and the cystic wall to be identified, achieving complete resection.

• Authors: Rafael García Moreno, Hyaissa Ippolito Bastidas, Ignacio Fernández Portales, Alejandro Rubio Fernández, María Hidalgo Llorca, José Manuel Cabezudo Artero
• Journal: British journal of neurosurgery (Br J Neurosurg) Vol. 37 Issue 5 Pg. 1223-1227 (Oct 2023) ISSN: 1360-046X [Electronic] England
• PMID: 33095079 (Publication Type: Case Reports, Journal Article)

Chemical References

• Aminolevulinic Acid
• 5-amino levulinic acid

Topics

• Humans
• Aged
• Meningioma (diagnostic imaging, surgery, pathology)
• Aminolevulinic Acid
• Meningeal Neoplasms (diagnostic imaging, surgery, pathology)
• Fluorescence