The efficacy of rotational pharmaco-mechanical thrombectomy in patients with acute iliofemoral deep vein thrombosis: Is the standard treatment of deep vein thrombosis changing?

Abstract

OBJECTIVE:

In this study, we aimed to evaluate the efficiency of rotational thrombectomy device in pharmaco-mechanical thrombolysis for symptomatic acute ilio-femoral deep vein thrombosis.

MATERIALS AND METHODS:

Between August 2013 and May 2018,82 patients with acute deep vein thrombosis comprising the iliofemoral segment whom underwent Pharmaco-mechanical thrombolysis were evaluated retrospectively. The Cleaner thrombectomy device was used. The resolution of thrombi was examined and graded. Development of post-thrombotic syndrome was assessed with Villalta scores.

RESULTS:

75 patients (91.4%) had complete thrombus resolution. Between 50-99% resolution was noted in 6 patients (7.4%) and in one (1.2%) case less than %50 thrombus resolution was obtained. Seventy-five patients (91%) of the cohort could be treated in a single session; 7 patients (8.6%) required reintervention(s). Although improved post-thrombotic syndrome rates were lower at the short term, Villalta scores gradually increased during follow up.

CONCLUSIONS:

In conclusion, Pharmaco-mechanical thrombolysis with Cleaner thrombectomy device is a safe and beneficial method for the treatment of acute iliofemoral deep vein thrombosis. Long term follow up data of large volume multicenter studies are warranted.

• Authors: Orhan Rodoplu, Cenk Eray Yildiz, Didem Melis Oztas, Metin Onur Beyaz, Mustafa Ozer Ulukan, Orcun Unal, Cenk Conkbayir, Murat Ugurlucan
• Journal: Phlebology (Phlebology) Vol. 36 Issue 2 Pg. 119-126 (Mar 2021) ISSN: 1758-1125 [Electronic] England
• PMID: 33092483 (Publication Type: Journal Article)

Topics

• Femoral Vein
• Humans
• Iliac Vein (diagnostic imaging)
• Retrospective Studies
• Thrombectomy
• Thrombolytic Therapy
• Treatment Outcome
• Vascular Patency
• Venous Thrombosis (drug therapy)