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Radiologic response to MEK inhibition in a patient with a WNT-activated craniopharyngioma.

AuthorsKrupesh Patel, Jeffrey Allen, David Zagzag, Jeffrey Wisoff, Alireza Radmanesh, Tatyana Gindin, Theodore Nicolaides
JournalPediatric blood & cancer (Pediatr Blood Cancer) Vol. 68 Issue 3 Pg. e28753 (03 2021) ISSN: 1545-5017 [Electronic] United States
PMID33073916 (Publication Type: Case Reports, Letter)
Chemical References
  • Benzimidazoles
  • Protein Kinase Inhibitors
  • WNT1 protein, human
  • Wnt1 Protein
  • binimetinib
  • MAP Kinase Kinase 1
  • MAP2K1 protein, human
Topics
  • Adult
  • Benzimidazoles (therapeutic use)
  • Craniopharyngioma (drug therapy, metabolism, pathology)
  • Female
  • Humans
  • MAP Kinase Kinase 1 (antagonists & inhibitors)
  • Magnetic Resonance Imaging (methods)
  • Pituitary Neoplasms (drug therapy, metabolism, pathology)
  • Protein Kinase Inhibitors
  • Wnt1 Protein (metabolism)

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