Abstract | BACKGROUND: METHODS: We retrospectively analyzed 131 consecutive persistent AF patients with valvular heart diseases who were followed up 3 months after RF maze procedure. Their clinical data were recorded. Logistic regression analyses were performed for significant predictors. Receiver operating characteristic analysis was used for validation with corresponding area under the curve. RESULTS: 70 (53.4%) patients experienced early recurrence after procedure. Patients with early recurrence were older, have longer AF duration history, larger left atria diameter (LAD), higher plasma C-reactive protein (CRP), lower triglycerides (TG), lower cholesterol (TC), increased monocyte counts, lower HDL cholesterol, and increased M/H ratio. In multivariate analysis, age (OR 1.1 95% CI 1.0-1.1 P = .003), LAD (OR 2.1, 95%CI 1.2-3.5, P = .006), TG (OR 0.35, 95% CI 0.15-0.84, P = .019), M/H (OR 6.1, 95% CI 2.9-13.0, P < .001) were significantly independent predictors of AF early recurrence. M/H ratio demonstrated a significant predictive value (AUC = 0.77, sensitivity 89.0%, specificity 54%). Further, there was a positive correlation of M/H ratio with CRP and white blood cell. CONCLUSION: Preoperative M/H ratio was an independent risk factor of AF early recurrence following RF maze operation. M/H ratio should be considered in prediction of early recurrence for valvular AF patients.
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Authors | Ailiya Adili, Yali Wang, Xiyu Zhu, Hailong Cao, Fudong Fan, Xinlong Tang, Qing Zhou, Dongjin Wang |
Journal | Journal of clinical laboratory analysis
(J Clin Lab Anal)
Vol. 35
Issue 2
Pg. e23595
(Feb 2021)
ISSN: 1098-2825 [Electronic] United States |
PMID | 32978843
(Publication Type: Journal Article)
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Copyright | © 2020 The Authors. Journal of Clinical Laboratory Analysis Published by Wiley Periodicals LLC. |
Chemical References |
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Topics |
- Aged
- Atrial Fibrillation
(blood, etiology, surgery)
- Cholesterol, HDL
(blood)
- Female
- Humans
- Male
- Maze Procedure
- Middle Aged
- Monocytes
(physiology)
- Multivariate Analysis
- Preoperative Period
- Prognosis
- ROC Curve
- Risk Factors
- Treatment Outcome
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