Abstract | BACKGROUND: METHODS: The study was a 12-week, double-blind, randomized, controlled, parallel intervention study. We randomized 73 subjects with abdominal obesity to 1 of 4 iso-energetic dietary interventions: 60 g per day of either WP hydrolysate or maltodextrin (MD) combined with high-fiber (HiFi; 30 g dietary fiber/day) or low-fiber (LoFi; 10 g dietary fiber/day) cereal products. We assessed changes in insulin sensitivity, gut hormones ( GLP-1, GLP-2, GIP, and peptide YY), body composition, 24-h BP, resting energy expenditure and respiratory exchange ratio (RER), and appetite. RESULTS: Sixty-five subjects completed the trial. Subjective hunger ratings were lower after 12 weeks of WP compared with MD, independent of fiber content (P = 0.02). We found no effects on ratings of satiety, fullness or prospective food consumption for either of the interventions. Intake of WP combined with LoFi increased the postprandial peptide YY response. There were no effects of WP or fiber on insulin sensitivity, body composition, energy expenditure, incretins, or 24-h BP. CONCLUSIONS:
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Authors | Rasmus Fuglsang-Nielsen, Elin Rakvaag, Bente Langdahl, Knud Erik Bach Knudsen, Bolette Hartmann, Jens Juul Holst, Kjeld Hermansen, Søren Gregersen |
Journal | European journal of clinical nutrition
(Eur J Clin Nutr)
Vol. 75
Issue 4
Pg. 611-619
(04 2021)
ISSN: 1476-5640 [Electronic] England |
PMID | 32948867
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
- Blood Glucose
- Dietary Fiber
- Insulin
- Whey Proteins
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Topics |
- Appetite
- Blood Glucose
- Blood Pressure
- Body Composition
- Cross-Over Studies
- Dietary Fiber
- Energy Intake
- Energy Metabolism
- Humans
- Insulin
- Insulin Resistance
- Obesity, Abdominal
- Prospective Studies
- Whey Proteins
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