Abstract | PURPOSE: To evaluate the efficacy of transscleral drainage of subretinal fluid (TDSRF) with and without pars plana vitrectomy (PPV), which are performed as an adjunct to ablative therapies in advanced Coats disease. DESIGN: Retrospective, comparative case series. PATIENT POPULATION: A total of 31 eyes from 31 consecutive patients with advanced Coats disease at an average age of 47.8 ± 34.2 (2-156) months at the time of the surgery, who underwent TDSRF alone or in combination with PPV. METHODS: RESULTS: Sixteen patients underwent TDSRF alone, and 15 patients underwent combined TDSRF and PPV. Mean follow-up time was 34.8 ± 32.9 months (6-128). Anatomical success rate of combined TDSRF and PPV was higher than that of TDSRF alone (93.8% vs 75%, respectively). The incidence of epiretinal membrane formation, number of laser photocoagulation procedures, and anti- VEGF treatments were statistically significantly higher in the group that underwent TDSRF alone than in those who had combined TDSRF and PPV in the long term. There was an improvement in vision in only 4 eyes (12.9%) (all >3 years old at presentation) during the follow-up. CONCLUSIONS: Combined TDSRF and PPV appears to be more effective in controlling the disease than TDSRF alone, as an adjunct to ablative procedures for the treatment of advanced Coats disease. The need for additional treatment is much less with the addition of PPV.
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Authors | Ahmet Yucel Ucgul, Sengul Ozdek, Mestan Ertop, Hatice Tuba Atalay |
Journal | American journal of ophthalmology
(Am J Ophthalmol)
Vol. 222
Pg. 6-14
(02 2021)
ISSN: 1879-1891 [Electronic] United States |
PMID | 32918903
(Publication Type: Comparative Study, Journal Article)
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Copyright | Copyright © 2021 Elsevier Inc. All rights reserved. |
Topics |
- Child, Preschool
- Drainage
(methods)
- Female
- Humans
- Male
- Retinal Telangiectasis
(surgery)
- Retrospective Studies
- Visual Acuity
- Vitrectomy
(methods)
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