Abstract | SCOPE: METHODS AND RESULTS: CONCLUSION:
Gluten ingestion has no specific effect on epithelial integrity or symptoms in this cohort, but reducing FODMAP intake concomitantly reduces symptoms and reverses apparent colonic epithelial injury. These findings highlight the heterogeneity of populations self-reporting gluten sensitivity and implicate FODMAPs in colonic injury in IBS.
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Authors | Mary Ajamian, Gennaro Rosella, Evan D Newnham, Jessica R Biesiekierski, Jane G Muir, Peter R Gibson |
Journal | Molecular nutrition & food research
(Mol Nutr Food Res)
Vol. 65
Issue 5
Pg. e1901275
(03 2021)
ISSN: 1613-4133 [Electronic] Germany |
PMID | 32902928
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Copyright | © 2020 Wiley-VCH GmbH. |
Chemical References |
- Acute-Phase Proteins
- CD14 protein, human
- Carrier Proteins
- Lipopolysaccharide Receptors
- Membrane Glycoproteins
- SDC1 protein, human
- Syndecan-1
- lipopolysaccharide-binding protein
- Glutens
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Topics |
- Acute-Phase Proteins
- Adult
- Carrier Proteins
(blood)
- Celiac Disease
(etiology)
- Diet, Carbohydrate-Restricted
- Double-Blind Method
- Female
- Glutens
(administration & dosage)
- Humans
- Irritable Bowel Syndrome
(diet therapy, etiology)
- Lipopolysaccharide Receptors
(blood)
- Malabsorption Syndromes
(diet therapy, etiology)
- Male
- Membrane Glycoproteins
(blood)
- Middle Aged
- Self Report
- Syndecan-1
(blood)
- Treatment Outcome
- Young Adult
|