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Liver Transplantation in a Patient With Acute-on-Chronic Liver Failure Due to Traditional Chinese Medicine Intoxication Using Donation After Circulatory Death From a Renal Transplant Recipient: A Case Report.

Abstract
Acute-on-chronic liver failure (ACLF) is a clinical manifestation of acute liver failure and decompensation on the basis of chronic liver disease. To date, hepatitis B virus-related ACLF is still the main cause of liver failure in China. Liver transplantation is currently the most likely treatment option to cure ACLF, but the shortage of donor livers is a barrier to its widespread use. The shortage of organs has led to increased use of expanded-criteria donors (ECDs), that is, donation after cardiac death (DCD) and its variant donation after brain and cardiac death (DBCD-China, DCBD-Switzerland). Here we report a case of liver transplantation, whose recipient was diagnosed with ACLF as a result of use of traditional Chinese medicine while the donor liver was retrieved from a renal transplant patient 4 years after transplantation. This transplant was carried out in accordance with the Helsinki Congress and the Declaration of Istanbul.
AuthorsYafei Guo, Zebin Zhu, Wei Wu, Dehao Huang, Hao Zheng, Zhijun Xu, Xuefeng Li, Ning Wang, Jiwei Qin, Yang Liu, Lianxin Liu, Björn Nashan
JournalTransplantation proceedings (Transplant Proc) Vol. 52 Issue 9 Pg. 2813-2816 (Nov 2020) ISSN: 1873-2623 [Electronic] United States
PMID32900476 (Publication Type: Case Reports, Journal Article)
CopyrightCopyright © 2020 The Author(s). Published by Elsevier Inc. All rights reserved.
Topics
  • Acute-On-Chronic Liver Failure (chemically induced, surgery)
  • Death
  • Female
  • Graft Survival
  • Humans
  • Kidney Transplantation
  • Liver Transplantation (methods)
  • Medicine, Chinese Traditional (adverse effects)
  • Middle Aged
  • Retrospective Studies
  • Tissue Donors (supply & distribution)

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