Abstract | BACKGROUND: CASE SUMMARY: An 80-year-old Japanese woman presented with a 7-mo history of a tingling sensation in the lower limbs. She also presented with various other symptoms such as pancytopenia, high fever daily, and unconsciousness with hypoglycemia. Although the doctor who previously treated her diagnosed hypoglycemia as being due to hypopituitarism, the cause of the other symptoms remained uncertain despite a 7-mo evaluation period. We performed bone marrow aspiration to evaluate pancytopenia and found that she had hemophagocytic lymphohistiocytosis (HLH). On the basis of a random skin biopsy for assessing the cause of HLH, she was diagnosed with intravascular B-cell lymphoma. HLH and hypopituitarism were considered secondary to IVL. All her clinical findings matched the presentations of IVL. She was immediately treated with chemotherapy and achieved complete response. She was relapse free two years after treatment. CONCLUSION: IVL should be included in the differential diagnosis of hypopituitarism, which although life-threatening, is treatable through prompt diagnosis and appropriate chemotherapy.
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Authors | Teiko Kawahigashi, Shinichi Teshima, Eri Tanaka |
Journal | World journal of clinical oncology
(World J Clin Oncol)
Vol. 11
Issue 8
Pg. 673-678
(Aug 24 2020)
ISSN: 2218-4333 [Print] United States |
PMID | 32879852
(Publication Type: Case Reports)
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Copyright | ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |