[A Case of Rectal Neuroendocrine Carcinoma Treated with Multidisciplinary Therapy but with a Poor Prognosis].

Abstract

A 70-year-old man presented to our hospital with weight loss. A colonoscopy revealed advanced cancer in the lower rectum. Computed tomography showed a tumor larger than 5 cm in the lower rectum with metastasis to the right lateral lymph node. The patient was diagnosed with advanced locally rectal cancer, and chemoradiotherapy(35 Gy plus S-1)was added after 6 courses of mFOLFOX6, and laparoscopic abdominal perineal resection and right lateral lymph nodes dissection were performed. Histopathological examination revealed endocrine cell carcinoma(pT3[A], pN0, M0, pStage Ⅱa). Four months after the operation, recurrence was found in the pelvis, lymph nodes, and lungs, and he died 9 months after the operation. Neuroendocrine carcinoma is relatively rare, so the further accumulation of cases and establishment of treatment methods are desired.

• Authors: Manabu Kurayoshi, Masahiro Nakahara, Hiroshi Okuda, Yukitoshi Shidahara, Ryosuke Hirohata, Kosuke Ono, Fumihiro Hirata, Tomoyuki Abe, Nobuaki Fujikuni, Tatsunari Sasada, Minoru Yamaki, Hironobu Amano, Toshio Noriyuki
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 47 Issue 8 Pg. 1261-1263 (Aug 2020) ISSN: 0385-0684 [Print] Japan
• PMID: 32829369 (Publication Type: Case Reports, Journal Article)

Topics

• Aged
• Carcinoma, Neuroendocrine
• Humans
• Male
• Neoplasm Recurrence, Local
• Prognosis
• Rectal Neoplasms
• Rectum