Abstract | BACKGROUND: Scalp conditions are often multifactorial. OBJECTIVE: To characterize patients with scalp involvement and patch-testing outcomes. METHODS: Retrospective cross-sectional analysis of North American Contact Dermatitis Group data (1996-2016). Study groups included patients with scalp involvement (≤3 anatomic sites coded) with or without additional sites. RESULTS: A total of 4.8% of patients (2331/48,753) had scalp identified as 1 of up to 3 affected anatomic sites. Approximately one-third of "scalp-only" individuals had a specific primary diagnosis of allergic contact dermatitis (38.6%), followed by seborrheic dermatitis (17.2%) and irritant contact dermatitis (9.3%). When adjacent anatomic sites were affected, allergic contact dermatitis was more frequently identified as the primary diagnosis (>50%). The top 5 currently clinically relevant allergens in scalp-only patients were p-phenylenediamine, fragrance mix I, nickel sulfate, balsam of Peru, and cinnamic aldehyde. Methylisothiazolinone sensitivity was notable when adjacent anatomic sites were involved. The top 3 specifically identified sources for scalp-only allergens were hair dyes, shampoo/conditioners, and consumer items (eg, hair appliances, glasses). LIMITATIONS: Tertiary referral population. CONCLUSION:
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Authors | Erin M Warshaw, Sara A Kullberg, Joel G DeKoven, Howard I Maibach, Donald V Belsito, Jonathan I Silverberg, Joseph F Fowler Jr, Amber R Atwater, Denis Sasseville, Margo J Reeder, James S Taylor, Vincent A DeLeo, Melanie D Pratt, Kathryn A Zug, Anthony F Fransway |
Journal | Journal of the American Academy of Dermatology
(J Am Acad Dermatol)
Vol. 84
Issue 4
Pg. 977-988
(Apr 2021)
ISSN: 1097-6787 [Electronic] United States |
PMID | 32822786
(Publication Type: Journal Article)
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Copyright | Published by Elsevier Inc. |
Chemical References |
- Allergens
- Hair Dyes
- Hair Preparations
- Irritants
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Topics |
- Adult
- Aged
- Allergens
(adverse effects)
- Canada
(epidemiology)
- Cross-Sectional Studies
- Dermatitis, Allergic Contact
(epidemiology, etiology, pathology)
- Dermatitis, Atopic
(epidemiology, etiology, pathology)
- Dermatitis, Irritant
(epidemiology, etiology, pathology)
- Dermatitis, Seborrheic
(epidemiology, etiology, pathology)
- Eyeglasses
- Female
- Hair Dyes
(adverse effects)
- Hair Preparations
(adverse effects)
- Humans
- Irritants
(adverse effects)
- Male
- Middle Aged
- Organ Specificity
- Patch Tests
- Retrospective Studies
- Scalp Dermatoses
(epidemiology, etiology, pathology)
- United States
(epidemiology)
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