Abstract | OBJECTIVE: METHODS: Newborns with severe acute respiratory distress syndrome aged 0-28 days and gestational age ≥36 weeks were included in the study if their cases were managed with non-extra corporal membrane oxygenation treatments. Patients were divided into two groups according to whether they died before discharge. Predictors of non-extra corporal membrane oxygenation treatment failure were sought, and the threshold of predictors was calculated. RESULTS: A total of 103 patients were included in the study. A total of 77 (74.8%) survived hospitalization and were discharged, whereas 26 (25.2%) died. Receiver operating characteristic analysis of oxygen index, pH, base excess, and combinations of these indicators demonstrated the advantage of the combination of oxygen index and base excess over the others variables regarding their predictive ability. The area under the curve for the combination of oxygen index and base excess was 0.865. When the cut-off values of oxygen index and base excess were 30.0 and -7.4, respectively, the sensitivity and specificity for predicting death were 77.0% and 84.0%, respectively. The model with base excess added a net reclassification improvement of 0.090 to the model without base excess. CONCLUSION:
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Authors | Hui Wu, Xiaoyang Hong, Yangming Qu, Zhenqiu Liu, Zhe Zhao, Change Liu, Qiong Ji, Jie Wang, Quan Xueli, Sun Jianwei, Dongliang Cheng, Zhi-Chun Feng, Shi Yuan |
Journal | Jornal de pediatria
(J Pediatr (Rio J))
2021 Jul-Aug
Vol. 97
Issue 4
Pg. 409-413
ISSN: 1678-4782 [Electronic] Brazil |
PMID | 32822669
(Publication Type: Journal Article)
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Copyright | Copyright © 2020. Published by Elsevier Editora Ltda. |
Chemical References |
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Topics |
- Humans
- Infant
- Infant, Newborn
- Oxygen
- Oxygen Inhalation Therapy
- Respiratory Distress Syndrome
(therapy)
- Respiratory Distress Syndrome, Newborn
(therapy)
- Respiratory Insufficiency
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