The safety and efficacy of the LVIS stent for the treatment of ruptured intracranial aneurysms within 24 hours: A multicenter retrospective study.

Abstract

OBJECTIVE:

Stent-assisted coiling is increasingly used in the treatment of acutely ruptured intracranial aneurysms. However, the optimal timing of the stent-assisted coiling remains unknown. We aimed to investigate the safety and efficacy of the Low Profile Visualized Intraluminal Support (LVIS) stent for ruptured aneurysms treatment within 24 h comparing to the treatment between 25 and 72 h of symptom onset.

PATIENTS AND METHODS:

We conducted a multicenter retrospective study on 110 consecutive patients with ruptured intracranial aneurysms. These patients were treated with LVIS stent within 72 h in four tertiary hospitals between January 2017 and December 2017. The timing of treatment was grouped into the treatment within 24 h and the treatment between 25 and 72 h. Baseline characteristics, periprocedural complications, angiographic results, and clinical outcomes were compared between the two groups.

RESULTS:

A total of 101 patients were included. 49 (48.5 %) patients were treated within 24 h and 52 (51.5 %) within between 25 and 72 h. Periprocedural complications occurred in 2 (4.1 %) patients treated within 24 h compared with those in 10 (19.2 %) treated between 25-72 h (P = 0.032). No early rebleeding occurred in both groups. 45 (91.8 %) of 49 aneurysms had complete occlusion on immediate angiography compared with 46 (88.5 %) of 52 aneurysms had complete occlusion. 2 (2.0 %) aneurysms were retreated. The clinical outcomes and angiographic results did not differ between the two groups.

CONCLUSIONS:

The LVIS stent-assisted coiling may be safe and effective in the treatment of selected patients with ruptured aneurysms within 24 h of symptom onset.

• Authors: Xianggan Wang, Haixia Xing, Jing Cai, Dianshi Jin, Yongchun Chen, Yudi Cui, Shenghao Ding, Jieqing Wan, Yaohua Pan, Guohua Mao, Bing Zhao
• Journal: Clinical neurology and neurosurgery (Clin Neurol Neurosurg) Vol. 197 Pg. 106117 (10 2020) ISSN: 1872-6968 [Electronic] Netherlands
• PMID: 32745790 (Publication Type: Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't)
• Copyright: Copyright © 2020 Elsevier B.V. All rights reserved.

Topics

• Adult
• Aged
• Aged, 80 and over
• Aneurysm, Ruptured (surgery)
• Embolization, Therapeutic (adverse effects, methods)
• Endovascular Procedures (adverse effects, methods)
• Female
• Humans
• Intracranial Aneurysm (surgery)
• Male
• Middle Aged
• Retrospective Studies
• Stents (adverse effects)
• Treatment Outcome