Abstract | BACKGROUND: Family integrated care (FIC), originating from the neonatal intensive care unit, has proved to be an effective therapy for the care of several diseases in adults. However, it is still unclear whether it is successful in the treatment of refractory cancer-related pain using an intrathecal morphine pump ( IMP). METHODS: A prospective study was performed to enroll patients with refractory cancer-related pain treated by IMP. Medical records, including demographic data, types of cancer, doses of opioids before the implantation, were gathered at baseline. Besides, numerical pain rating scales (NRS) were measured to assess the severity of pain. Karnofsky performance scores (KPS), self-rating anxiety scale (SAS) scores and selfrating depression scale (SDS) scores were used to assess the physical and psychological status of patients. Follow-up lasted for at least 12 months. The changes in NRS, KPS, SAS, and SDS scores were recorded, as well as adverse events and survival rates. RESULTS: Totally, 33 patients were enrolled and divided into traditional care groups and FIC groups. The results showed that the implantation of IMP relieved the pain in both groups. Moreover, patients in the FIC group had significantly more relief of pain than those in the traditional group (P=0.04). Similarly, KPS raised more, and scores of SAS and SDS decreased more in the FIC group. Besides, fewer adverse events occurred in the FIC group, but the survival rate showed no significant difference between the two groups. CONCLUSIONS: FIC enhances the effects of IMP on the relief of refractory cancer-related pain and improves the physical and psychological status of patients.
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Authors | Yan Cheng, Lina Wang, Ziying Zha, Xiangqin Zhao |
Journal | Annals of palliative medicine
(Ann Palliat Med)
Vol. 9
Issue 4
Pg. 2163-2170
(Jul 2020)
ISSN: 2224-5839 [Electronic] China |
PMID | 32692232
(Publication Type: Journal Article)
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Chemical References |
- Analgesics, Opioid
- Morphine
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Topics |
- Adult
- Analgesics, Opioid
(therapeutic use)
- Cancer Pain
(drug therapy)
- Cohort Studies
- Delivery of Health Care, Integrated
- Humans
- Infant, Newborn
- Morphine
(therapeutic use)
- Neoplasms
(drug therapy)
- Prospective Studies
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