Abstract | BACKGROUND: METHODS: This study was a double-blinded randomized controlled trial. Twenty-eight individuals with chronic stroke received one of the following three interventions: (1) sequentially combined tDCS with MT (SEQ), (2) concurrently combined tDCS with MT (CON), and (3) sham tDCS with MT ( SHAM). Participants received interventions for 90 min/day, 5 days/week for 4 weeks. Daily function was assessed using the Nottingham Extended Activities of Daily Living Scale. Upper extremity motor function was assessed using the Fugl-Meyer Assessment Scale. Upper extremity motor control was evaluated using movement kinematic assessments. RESULTS: There were significant differences in daily function between the three groups. The SEQ group had greater improvement in daily function than the CON and SHAM groups. Kinematic analyses showed that movement time of the paretic hand significantly reduced in the SEQ group after interventions. All three groups had significant improvement in motor function from pre-intervention to post-intervention. CONCLUSION: The timing of tDCS with MT may influence restoration of daily function and movement efficiency of the paretic hand in chronic stroke patients. Sequentially applying tDCS prior to MT seems to be advantageous for enhancing daily function and hand movement control, and may be considered as a potentially useful strategy in future clinical application. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT02827864 . Registered on 29th June, 2016.
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Authors | Wan-Wen Liao, Wei-Chi Chiang, Keh-Chung Lin, Ching-Yi Wu, Chien-Ting Liu, Yu-Wei Hsieh, Yun-Chung Lin, Chia-Ling Chen |
Journal | Journal of neuroengineering and rehabilitation
(J Neuroeng Rehabil)
Vol. 17
Issue 1
Pg. 101
(07 20 2020)
ISSN: 1743-0003 [Electronic] England |
PMID | 32690032
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Topics |
- Activities of Daily Living
- Adult
- Aged
- Biomechanical Phenomena
- Combined Modality Therapy
(methods)
- Female
- Humans
- Male
- Middle Aged
- Physical Therapy Modalities
- Pilot Projects
- Recovery of Function
- Stroke
(physiopathology)
- Stroke Rehabilitation
(methods)
- Transcranial Direct Current Stimulation
(methods)
- Upper Extremity
(physiopathology)
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