Abstract | BACKGROUND: Saline groundwater, collected from the east coast of Korea, has been shown to have protective effects against 2,4-dinitrochlorobenzene- ( DNCB-) induced atopic dermatitis-like skin lesions in the murine model. OBJECTIVES: METHODS: Twenty-four subjects with mild-to-moderate atopic dermatitis were instructed to take a bath in saline groundwater solution for 20 minutes per day for two weeks. Evaluations were performed at baseline and week 2, including SCORing Atopic Dermatitis (SCORAD) index, corneometry, transepidermal water loss, visual analogue scale for pruritus, and collection of adverse events. RESULTS: Subjects showed significant improvement with respect to the SCORAD index, skin hydration, transepidermal water loss, and pruritus at week 2 when compared with the baseline. CONCLUSION:
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Authors | Jisook Yoo, Ji Young Choi, Bo Young Lee, Chang Ho Shin, Jung-Won Shin, Chang Hun Huh, Jung-Im Na |
Journal | Evidence-based complementary and alternative medicine : eCAM
(Evid Based Complement Alternat Med)
Vol. 2020
Pg. 8303716
( 2020)
ISSN: 1741-427X [Print] United States |
PMID | 32595740
(Publication Type: Journal Article)
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Copyright | Copyright © 2020 Jisook Yoo et al. |