Abstract |
Stimulator of interferon genes is an important innate immune signaling molecule in the body and is involved in the innate immune signal transduction pathway induced by pathogen-associated molecular patterns or damage-associated molecular patterns. Stimulator of interferon genes promotes the production of type I interferon and thus plays an important role in the innate immune response to infection. In addition, according to a recent study, the stimulator of interferon genes pathway also contributes to anti-inflammatory and anti- tumor reactions. In this paper, current researches on the Stimulator of interferon genes signaling pathway and its relationship with tumor immunity are reviewed. Meanwhile, a series of critical problems to be addressed in subsequent studies are discussed as well.
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Authors | Yuanjin Gong, Chang Chang, Xi Liu, Yan He, Yiqi Wu, Song Wang, Chongyou Zhang |
Journal | Current pharmaceutical design
(Curr Pharm Des)
Vol. 26
Issue 26
Pg. 3085-3095
( 2020)
ISSN: 1873-4286 [Electronic] United Arab Emirates |
PMID | 32520678
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | Copyright© Bentham Science Publishers; For any queries, please email at [email protected]. |
Chemical References |
- Interferon Type I
- Membrane Proteins
- Nucleotidyltransferases
|
Topics |
- Humans
- Immunity, Innate
- Interferon Type I
- Membrane Proteins
- Nucleotidyltransferases
(metabolism)
- Signal Transduction
|