Abstract | INTRODUCTION: AREAS COVERED: This article reviews the current literature on polatuzumab vedotin, including its pharmacology, as well as summarizing the results of clinical trials in relapsed/refractory diffuse large B-cell lymphoma (DLBCL) as a single agent and in combination with other chemotherapies and chemoimmunotherapies. The current landscape of approved therapies for relapsed and refractory DLBCL, as well as other promising novel approaches, is discussed. EXPERT OPINION:
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Authors | Mary-Kate Malecek, Marcus P Watkins, Nancy L Bartlett |
Journal | Expert opinion on biological therapy
(Expert Opin Biol Ther)
Vol. 21
Issue 7
Pg. 831-839
(07 2021)
ISSN: 1744-7682 [Electronic] England |
PMID | 32500753
(Publication Type: Journal Article, Review)
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Chemical References |
- Antibodies, Monoclonal
- Immunoconjugates
- polatuzumab vedotin
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Topics |
- Antibodies, Monoclonal
(therapeutic use)
- Antineoplastic Combined Chemotherapy Protocols
(adverse effects)
- Hematopoietic Stem Cell Transplantation
- Humans
- Immunoconjugates
(therapeutic use)
- Lymphoma, Large B-Cell, Diffuse
(drug therapy)
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