Abstract | OBJECTIVE: METHODS: RESULTS: AR status was positive in 73% of meningiomas in the intracranial group, 87% of meningiomas in the CPA group, and in all meningiomas in the spinal group. Estrogen status was positive in only 7% of meningiomas in the intracranial group and in only 3% of meningiomas in the CPA group but in 30% of meningiomas in the spinal group. PR status was positive in 90% of meningiomas in the intracranial group, in 97% of meningiomas in the CPA group, and in 87% of meningiomas in the spinal group. These specific hormonal receptor statuses based on immunoreactive score were reflected on staining intensities. Furthermore, AR and PR expression was correlated in each group. CONCLUSIONS:
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Authors | Sylvain Portet, Tania Banor, Jonathan Bousquet, Adrien Simonneau, Marie Flores, Pierre Ingrand, Serge Milin, Lucie Karayan-Tapon, Benoit Bataille |
Journal | World neurosurgery
(World Neurosurg)
Vol. 140
Pg. e87-e96
(08 2020)
ISSN: 1878-8769 [Electronic] United States |
PMID | 32371078
(Publication Type: Journal Article, Observational Study)
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Copyright | Copyright © 2020 Elsevier Inc. All rights reserved. |
Chemical References |
- Receptors, Androgen
- Receptors, Estrogen
- Receptors, Progesterone
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Topics |
- Aged
- Cohort Studies
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Male
- Meningeal Neoplasms
(genetics, metabolism, pathology)
- Meningioma
(genetics, metabolism, pathology)
- Middle Aged
- Receptors, Androgen
(biosynthesis, genetics)
- Receptors, Estrogen
(biosynthesis, genetics)
- Receptors, Progesterone
(biosynthesis, genetics)
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