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Central Nervous System as Possible Site of Relapse in ERBB2-Positive Metastatic Colorectal Cancer: Long-term Results of Treatment With Trastuzumab and Lapatinib.

AuthorsAndrea Sartore-Bianchi, Sara Lonardi, Massimo Aglietta, Cosimo Martino, Fortunato Ciardiello, Silvia Marsoni, Salvatore Siena
JournalJAMA oncology (JAMA Oncol) Vol. 6 Issue 6 Pg. 927-929 (06 01 2020) ISSN: 2374-2445 [Electronic] United States
PMID32324210 (Publication Type: Clinical Trial, Clinical Trial, Phase II, Journal Article, Multicenter Study)
Chemical References
  • Antineoplastic Agents
  • Protein Kinase Inhibitors
  • Lapatinib
  • ERBB2 protein, human
  • Receptor, ErbB-2
  • Trastuzumab
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Antineoplastic Agents (therapeutic use)
  • Central Nervous System Neoplasms (radiotherapy, secondary, surgery)
  • Colorectal Neoplasms (drug therapy, metabolism, mortality, pathology)
  • Drug Resistance, Neoplasm
  • Female
  • Humans
  • Lapatinib (therapeutic use)
  • Male
  • Middle Aged
  • Protein Kinase Inhibitors (therapeutic use)
  • Receptor, ErbB-2 (metabolism)
  • Recurrence
  • Trastuzumab (therapeutic use)
  • Treatment Outcome

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