Pneumonia caused by coronavirus, which originated in Wuhan, China, in late 2019, has been spread around the world already becoming a pandemic. Unfortunately, there is not yet a specific
vaccine or effective
antiviral drug for treating
COVID-19. Many of these patients deteriorate rapidly and require intubation and are mechanically ventilated, which is causing the collapse of the health system in many countries due to lack of
ventilators and
intensive care beds. In this document we review two simple adjuvant
therapies to administer, without side effects, and low cost that could be useful for the treatment of acute severe
coronavirus infection associated with acute respiratory syndrome (SARS-CoV-2). VitaminC, a potent
antioxidant, has emerged as a relevant
therapy due to its potential benefits when administered intravenous. The potential effect of vitaminC in reducing
inflammation in the lungs could play a key role in
lung injury caused by
coronavirus infection. Another potential effective
therapy is
ozone: it has been extensively studied and used for many years and its effectiveness has been demonstrated so far in multiples studies. Nevertheless, our goal is not to make an exhaustive review of these
therapies but spread the beneficial effects themselves. Obviously clinical trials are necessaries, but due to the potential benefit of these two
therapies we highly recommended to add to the therapeutic arsenal.